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EMPLOYMENT SERVICE |
Research Associate Position in Natural Product Chemistry |
Department of Biological Sciences
Lehman College, City University of New York
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A research associate position is available immediately for a Ph.D.-level natural products chemist. The project involves providing phytochemical and bioavailability studies on botanicals undergoing preclinical and clinical study at the MSKCC NIH-sponsored Botanical Center. Candidates with extensive experience in the analysis, isolation, and structural elucidation of bioactive natural products will be given preference. Familiarity with bioavailability studies of natural products is considered a plus. The candidate must have experience in various chromatographic techniques including HPLC-PDA and LC-MS . The candidate will be expected to run and help to maintain laboratory equipment, including HPLC, LC-MS (LCQ iontrap and LCT-Premier Tof), and NMR. The candidate would be hired by MSKCC, and conduct phytochemical studies in my laboratory at City University of New York.
If interested, please respond directly to EDWARD.KENNELLY@lehman.cuny.edu
Posted 6 May 08
Lecturer in Organic or Biological (including medicinal and natural-products) Chemistry
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Department of Chemistry, University of Canterbury, Christchurch, New Zealand
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Applications are invited for a continuing position of Lecturer in Organic or Biological (including medicinal and natural products) Chemistry.
Applicants should have a Ph.D. and post-doctoral or equivalent experience, with demonstrated potential for excellent teaching and a record of high research productivity. The appointee will be required to teach and co-ordinate undergraduate and post-graduate courses in organic and/or biological chemistry, to contribute to teaching in other core areas, and to supervise graduate students.
The successful applicant should be able to inspire and motivate students and work within a collegial environment. She or he will be expected to publish regularly in high-impact journals and actively seek funding in support of research. The Department of Chemistry offers significant opportunities for collaborative and interdisciplinary research.
The appointee will work in one of the leading chemistry departments in Australasia (www.chem.canterbury.ac.nz). The Department has excellent laboratory and research facilities and is dedicated to excellence in teaching and research.
Vacancy number: A130-08J
Closing date: 16 June 2008
Enquiries of an academic nature may be made to Bryce Williamson, HOD and Chair of Selection Panel, at bryce.williamson@canterbury.ac.nz. For detailed information and to apply online visit http://vacancies.canterbury.ac.nz/.
Posted 5 May 08
Department of Medicinal Chemistry
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University of Kansas
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The Department of Medicinal Chemistry at the University of Kansas invites qualified candidates to submit applications for the position of full-time post doctoral researcher. These will be reviewed by individual faculty members and placed in a pool for consideration for one-year research positions in medicinal chemistry (with the possibility of renewal for one or more additional years).
Faculty in the department carry out research in medicinal chemistry as broadly defined, including the fields of drug design, metabolism, enzymology, computer modeling, synthesis, and protein crystallography. Specific information about the research activities in the Department of Medicinal Chemistry can be obtained at our website, www.medchem.ku.edu.
A Ph.D. and research training in medicinal chemistry, organic chemistry, natural products chemistry, or biochemistry; preferred candidates will also have a record of research accomplishments as reflected in publications in peer-review journals and presentations at scientific meetings.
Applicants should submit a curriculum vitae, a letter of interest, the names, addresses, e-mails, and telephone numbers of three references, and a statement of the specific area in which the applicant is qualified to conduct research. This material can be submitted online along with your application at https://jobs.ku.edu (search for position 00206735).
Applications will be accepted on an ongoing basis. All positions are contingent upon funding. The University of Kansas is an EO/AA Employer.
PhD position FWF-funded project
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Vienna University
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PhD Position(30h/week, 30 months)
A PhD position is available in a FWF-funded project at
BOKU-University of Natural Resources and Applied Life
Sciences in cooperation with Vienna University, the
Austrian Academy of Sciences and the Institute of
Development Studies at the University of Sussex,
Brighton.
You will be working within a team including several
months of field research in rural areas of Eastern
Africa (Uganda, Ethiopia).
Criteria:
* Must speak and write fluently English
* Social science degree with focus on social
studies of science (STS)
* Experience in field research (qualitative data
collection and analysis)
Requirements:
To be sent electronically to
KNOWING@groupwise.boku.ac.at
* Curriculum vitae
* Letter of intent explaining the personal
interest and motivation
* Affiliation and contact details of two persons,
who might give additional information about applicant.
* Please do NOT send certificates or publications.
More information about the project:
https://forschung.boku.ac.at/fis/suche.projekte_uebersicht?sprache_in=de&projekt_id_in=6992
Deadline: Application open until a successful
candidate has been identified
Vienna, 10 of April 2008
For more information contact: christian.vogl@boku.ac.at
Structural Analysis
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AMRI
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AMRI, a recognized leader in the provision of drug discovery services to customers in the pharmaceutical and biotechnology industries, has an employment opportunity for a Senior Research Scientist, Structural Analysis at our facilities in Bothell, WA.
The key responsibilities are the:
- Isolation and structure elucidation of natural products and synthetic compounds with the proficient use of HPLC and LC/MS instruments; and the
- Development of new LC methods to solve analytical problems.
The successful candidate will hold a Ph.D. in Natural Products chemistry or related field with two to five years of post graduate or equivalent industrial experience. Applicants must be proficient with the use of NMR instruments utilizing common 1 D and 2 D experiments. Experience with LC-NMR and capillary NMR is desirable. Strong leadership skills and prior supervisory experience is required.
AMRI offers a comprehensive benefits package, which includes health, dental, 401(k), and vacation benefits, as well as incentive programs that reward and recognize individual performance and its correlation to company success.
Please apply via our website:
www.amriglobal.com
Posted 4 April 08
Postdoctoral research positions in natural products chemistry and molecular genetics
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The Center for Drug Design University of Minnesota
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The Center for Drug Design at the University of Minnesota invites applications for 2 postdoctoral positions in bacterial natural products chemistry and molecular genetics with a focus on infectious disease and anti-cancer activities. Research will be conducted under the supervision of Professor Christine Salomon. For more information about the Center for Drug Design at UMN, please visit www.cdd.umn.edu
Position descriptions and qualifications:
1. Natural Products Chemistry position: Qualifications required: A recent Ph.D. in pharmacognosy, chemical biology or related field. This position requires extensive experience with isolation and structural characterization of natural products using standard chromatography and spectroscopic techniques including multi-dimensional NMR and LC-mass spectrometry. Experience in natural product synthesis, microbiology/fermentation and in vitro and cell based assays are desired, but not required.
2. Biochemistry/molecular genetics position: Qualifications required: A recent Ph.D. in biology, biochemistry, chemical biology or related field. This position requires experience with characterizing and engineering secondary metabolic pathways such as polyketide synthases and nonribosomal peptide synthetases. Candidates should have experience in enzyme kinetics, biochemistry and in vitro assay development. Experience in microbiology and natural products isolation are desired, but not required.
Both positions require excellent oral and written communication skills, as well as the ability to work as part of an interdisciplinary team.
Term of appointment: Both positions are available as one year contracts, with the possibility of extension for up to 3 years contingent upon funding.
Start date: June 2008 (open to negotiation)
Application procedure: Please send a cover letter describing your experience and interests, CV and names and contact info for at least 2 references to Christine Salomon. Electronic submissions are preferred, but applications can also be mailed.
Email attachments should be sent to csalomon@umn.edu with “postdoctoral position” in the subject line. Hard copies of applications can be sent to the address below.
Christine Salomon
Center for Drug Design
University of Minnesota
MMC 204, 7-146 PWB
516 Delaware St. SE
Minneapolis, MN 55455
The University of Minnesota is an equal opportunity employer.
Posted 28 March 2008
Postdoctoral Research Associate Natural Products
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University of the Sciences in Philadelphia with John R. Porter, PhD
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A position is available immediately for a Postdoctoral Research Associate with background/experience in natural products isolation, purification, and characterization of compounds from crude extracts. Background must include experience with LC, MS and NMR data acquisition and interpretation. Applicants must provide proof of experience showing qualification for the position. The position requires a PhD or comparable degree in chemistry, pharmacognosy, biological chemistry, biology, or related areas. This is a one-year position with a second year possible contingent upon continuing funding. Applicants should send letter, resumé/CV, transcript of institution showing highest degree, names of referees, and supporting documentation to (via e-mail, j.porter@usp.edu) John R. Porter, PhD, Department of Biological Sciences, University of the Sciences in Philadelphia, 600 S. 43rd Street, Philadelphia, PA 19104. Review of applications will begin immediately.
USP provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Background check will be required.
Posted 21 March 2008
Council for Responsible Nutrition (CRN)
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Washington, D.C
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The Council for Responsible Nutrition (CRN)*, a Washington, D.C.-based trade association representing dietary supplement manufacturers and suppliers, seeks a Vice President or Director to increase the awareness of the research base that supports the safety and benefits of dietary supplements and to use that science as the basis for influencing and responding to regulatory and legislative initiatives, activities and media coverage of dietary supplements.
Education and Experience
- Doctor of Philosophy in Nutrition, Pharmacology, Pharmacognosy, Toxicology, Organic Chemistry, Botany, or Natural Medicine
- Minimum five years relevant experience in the field
- Familiarity with current federal regulation of dietary supplements
- Previous dietary supplement industry or FDA experience preferred
- Excellent written communication (with some history of publication in peer reviewed journals) and excellent oral presentation skills
- Ability to multi-task and work in collegial, fast-paced, fluid environment as a team player with other staff and with member company representatives
Salary: mid $100,000s, commensurate with experience and publication record.
To apply, send cover letter, resume and references to: Gerry Satterfield, The Council for Responsible Nutrition, 1828 L Street, N.W., Suite 900, Washington, D.C. 20036, fax to (202) 204-7980; or email to gsatterfield@crnusa.org. No phone calls please.
Posted 13 March 2008
Research Associate/Senior Research Associate Natural Products Chemistry
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CUBIST PHARMACEUTICAL
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Position Summary
Cubist Pharmaceuticals is currently seeking a Research Associates/Senior Research Associate in our natural products chemistry group. The individual will work as part of our team to extract and purify antibacterial agents produced by microbial fermentation broths and/or semi-synthetic reaction mixtures at scale level from milligrams to kilograms.
Duties and Responsibilities
- Participate in the development of processes for the isolation, separation and purification of targeted compounds from various microbial sources and semi-synthetic reaction complex.
- Carry out experiments, participate in experimental design, and summarize results under limited supervision.
- Perform chemical analyses using chromatographic and spectroscopic methods.
- Prepare laboratory notebooks, technical reports, summaries, protocols, and quantitative analyses.
- Maintain personal and shared work areas and equipments in good condition.
- Carry out assigned shared laboratory housekeeping tasks.
Work Environment
DSP and Chemistry lab
Physical Demands
Lifting large containers with ~30 lbs
Qualifications
Education/Certification
- BS or MS degree in chemistry or a related discipline
Experience
- 2+ years experience with isolation of compounds from natural sources.
Knowledge, Skills, and Abilities
- Essential experience with relevant separation methods including centrifugation, liquid extractions, chromatography (preparative HPLC), selective precipitation, crystallization and tangential flow filtration methods.
- Experience with relevant analytical instrument & technique including chromatographic methods (LC, GC) and spectroscopic methods (LC-MS, NMR) is a plus.
- Energetic, well-trained and self-motivated individual.
- Willing to learn and implement modern experimental techniques.
- Strong communications skills; able to work effectively as part of a team.
- Excellent analytical, organizational and multi-tasking skills.
- Proficiency in writing and making oral presentations.
- Computer literacy, including Microsoft Office.
Please submit a cover letter, CV, and references via email to jian-qiao.gu@cubist.com. More information about Cubist Pharmaceuticals, Inc. and employee benefits can be found at www.cubist.com.
Posted 4 March 2008
GMP Clinical Manufacturing Associate
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Bionovo Emeryville, CA |
BioNovo is a publicly traded pharmaceutical company (NASDQ: BNVI) focusing on the discovery and development of drugs for cancer and women’s health.
BioNovo is seeking a GMP Clinical Manufacturing Associate with a BS/MS in bioscience or engineering with 1-3 years GMP bio-manufacturing or process development experience for our Emeryville, California facility. Candidate must be able to work under cGMP guidelines, have good record keeping skills with attention to detail. Candidate must demonstrate knowledge of basic laboratory and pharmaceutical production equipment including but not limited to: pumps, mixers, process tanks, incubators and analytical equipment. The candidate must have experience with pharmaceutical (i.e. solid/liquid extractions, liquid/liquid partitions, evaporation) and biotech (i.e. fermentation, purification) unit operations including knowledge of basic chemical and biological safety procedures. Applicant must have the ability to lift 40 lbs.
Incumbent must be able to apply quantitative analysis to analyze process performance, must be proficient in a variety of mathematical disciplines and be able to work with both the metric and USA standards of measurement. Successful applicants must be able to read English and follow detailed written instructions and have good verbal/written communication skills and good procedural writing skills.
The ideal individual will be willing to perform clerical/non-science related activities and other duties as assigned. Applicant must be personable, punctual, not high maintenance, honest, self motivated, independent but knows when to ask for help. Applicant must have demonstrated ability to work effectively and efficiently in a team environment.
Mandarin fluency (read and write) is a big plus. Candidate must have a valid CA driver’s license. Written and practical assessment will be required.
BioNovo is a publicly traded pharmaceutical company (NASDQ: BNVI) focusing on the discovery and development of drugs for cancer and women’s health.
Salary Range:$50,000+/year depending on experience.
Please submit a cover letter, CV, and references to Bionovo Inc, Human Resources Dept, 5858 Horton St Suite 375, Emeryville , CA 94608 or via email to careers@bionovo.com . More information about Bionovo and employee benefits can be found at www.bionovo.com.
Posted 3 March 2008
Natural Products Chemist
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The Walker Cancer Research Institute, Inc |
NATURAL PRODUCTS DRUG DISCOVERY. The Walker Cancer Research Institute, Inc., a non-profit organization dedicated to the discovery of natural product anticancer agents, announces an opening for a Ph.D. Natural Products Chemist or equivalent. Required duties will include: performing bioassay-guided fractionation, isolation, purification and structure determination, and performance of cell culture bioassays. Appointment is for one year with possibility of extension. Salary based on qualifications and experience. Please submit resume, list of publications, research accomplishments, two recent letters of recommendation and list of references to: Elsa Pilarinou, Director,
WCRI (Florida Division), 1634 Metropolitan Blvd., Tallahassee, FL 32308.
Posted 21 February 2008
Herbalife International
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Senior Manager Botanical Sciences |
Herbalife is a global nutrition and direct selling company. We offer high-quality weight management, nutritional supplements and skin care products that combine the best of science and nature for a lifetime of good health. Our products are sold by over 1.6 million independent distributors in 65 countries. We follow our vision of ‘changing people’s lives” by providing the best opportunity in direct selling and the best nutrition and weight-management products in the world. We are a public company listed on the NYSE. We have a global focus and pursue profitability vigorously. We strive to make our communities better places to live and work through efforts of the Herbalife Family Foundation Casa Herbalife program, to bring good nutrition to kids. With ethics as our top priority, we offer an environment where employees are focused, passion is fueled and your career can “LIFT OFF” to unparalleled opportunities. We await your creativity, passion and desire to learn. You will be challenged and developed – both professionally and personally.
Herbalife International is presently seeking the position of Senior Manager, Botanical Sciences.
Responsibilities include:
Assist VP of Scientific Affairs in the Management of Scientific Affairs projects related to botanical ingredients. Support rationalization and harmonization of inner nutrition portfolio. Support in the development of botanical products and ingredients. Substantiate safety and efficacy information of Herbalife products. Provide regulatory support for claim substantiation and documentation for inner and outer nutrition products. Support in crafting documentation related to the quality, marketing, safety, efficacy, and regulatory status of ingredients and products. Control data gathering and report presentation for ingredient/product requests. Assist in leading corporate effort to improve botanical raw material specifications and product. Ongoing support to R&D and QA teams for complete reformulation (discontinuation) of botanical products. Assist in the botanical ingredient evaluation at the Mark Hughes Laboratory. Participate in collaborative projects with academic centers and institutions.
Skills/Education/Experience:
- Master of Science (Ph.D preferred) in Pharmacognosy, Botany (Botanical Medicine), Nutrition, or Naturopathic Doctor.
- Minimum 5 years experience in the dietary supplement industry. Ideal candidate will have botanical science knowledge, botanical supplement formulation, or nutrition experience.
- Excellent communication skills.
- Ability to take initiative in identifying and resolving problems and carrying out responsibilities under general supervision.
- Ability to organize workload for effective implementation; must be able to simultaneously manage multiple projects.
- Strong results orientation with a high degree of attention to detail.
- Ability to function as an effective team leader.
- Team player
- Ability to adapt as the external environment and organization evolves
Herbalife offers a very competitive compensation and benefits package, bonus, tuition reimbursement, two weeks vacation and all the vitamin supplements you can devour.
To apply, please send resume to staffing6@herbalfie.com
Posted 19 February 2008
Marine Natural Product Drug Discovery Assistantships in Panama
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Institute of Advanced Scientific Investigations and High Technology Services |
We are looking for two upper-division undergraduate students or recent graduates for research assistantships in natural product drug discovery during the summer and/or fall of 2008 in the lab of Dr. Marcy J. Balunas at the Institute of Advanced Scientific Investigations and High Technology Services (INDICASAT) in conjunction with the Smithsonian Tropical Research Institute (STRI) in Panama City, Panama. The projects will be part of a U.S. National Institutes of Health (NIH) International Cooperative Biodiversity Group (ICBG) grant entitled “Ecologically Directed Drug Discovery in Panama” (Principal Investigator, Dr. William H. Gerwick, Scripps Institution of Oceanography).
Project Description
Treatments for tropical diseases are generally prohibitively expensive for many people living in areas of high rates of infection. Furthermore, many tropical diseases are developing resistance to currently available treatments, or are without effective treatments. Natural products contain highly diverse structures with unique characteristics not readily accessible through synthetic or combinatorial chemistry. Marine and plant species from the biologically diverse oceans in Panama will likely yield chemically diverse compounds, some of which may inhibit the infection and/or spread of tropical diseases. This project involves:
- Using ecologically guided marine collection techniques to collect specimens for screening;
- Extracting marine specimens, performing pre-fractionation of extracts, and sending for screening for in vitro activity against tropical diseases including malaria, Chagas’ disease, and leishmaniasis, as well as for cytotoxicity screening;
- Conducting bioassay-guided fractionation to isolate and identify compounds that act against these tropical diseases.
Students will be involved in many aspects of the research project, including collection, extraction, and bioassay-guided fractionation using various chromatographic and spectroscopic techniques.
Funding
Funding for these assistantships comes from the Minority Health and Health Disparities International Research Training (MHIRT) program funded through the National Center on Minority Health and Health Disparities (NCMHD). The MHIRT program is designed to increase the numbers of students belonging to health disparities populations or underrepresented minorities that pursue advanced degrees in basic sciences, biomedical or clinical research fields. Travel, food, lodging, and research expenses are completely covered and a small personal stipend is provided.
Program Eligibility:
- Students should belong to an ethnic minority including, but not limited to, African Americans, Hispanic Americans, Native Americans, Alaskan Natives, Native Hawaiians and Pacific Islanders, or rural Appalachians (non-ethnic females also qualify)
- Applicants must be U.S. citizens or permanent residents of the U.S.
- Students should be juniors, seniors, or recent graduates with a minimum GPA of 3.0
- Students should have completed at least one year of chemistry with laboratory
- Students must demonstrate interest in pursuing graduate research
- Students must spend a minimum of 3 months in Panama working on the project (4-6 months is preferred)
To Apply:
Send the following materials to Dr. Marcy J. Balunas at mbalunas@ucsd.edu:
- Curriculum Vitae including name, permanent and current addresses, phone, e-mail, GPA, and complete educational and employment history (social security number and date of birth will be required upon acceptance to the program).
- A 2-3 page essay including information on your background (e.g., family history, ethnicity, previous laboratory research, education, travel experience, etc.) and your career goals (including how you think a MHIRT assistantship will help you attain these goals).
- Two letters of recommendation, including from someone who has directly supervised you in a laboratory setting (e.g., graduate student, technician, postdoctoral researcher, or professor). Letters of recommendation should be e-mailed directly to Dr. Balunas.
DEADLINE FOR SUBMISSION: Application review will begin March 15, 2008 and continue until positions are filled.
Posted 14 February 2008
USDA Animal and Plant Health Inspection Service Riverdale, Maryland |
Director of Plant Pathology and Weed Programs
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A Director of Plant Pathology and Weed Programs is sought by the USDA Animal and Plant Health Inspection Service located in Riverdale, Maryland to provide " ... leadership in assigned domestic and emergency programs ... in establishing and maintaining collaborative relationships with State departments ... [To] Interact with Departmental, Federal, and State agencies, universities, not-for-profit organizations, and commercial organizations on survey, regulatory and control activities ... Directs, coordinates and evaluates assigned Plant Protection and Quarantine (PPQ) programs ... Keeps PPQ officials fully informed of program activities ... Participates ... in the development of program goals, objectives, budgets, strategic plans, and action plans ..." - The position opened on February 4 and closes on February 25, 2008 and is open to all United States citizens.
Document Title: The title of the USDA APHIS Position Announcement is "Director of Plant Pathology and Weed Programs"
Organization: USDA Animal and Plant Health Inspection Service, Plant Pathology and Weed Programs
Source: February 4, 2008 USDA APHIS Position Announcement
Applications Due By: February 25, 2008
Web site: The February 4, 2008 USDA APHIS position announcement is posted at
http://jobsearch.usajobs.gov/getjob.asp?JobID=68083327&brd=3876&AVSDM=2008%2D02%2D04+00%3A03%3A02&q=Supervisory+Agriculturist+Director+of+Plant+Patho&sort=rv&vw=d&Logo=0&FedPub=Y&lid=316&FedEmp=N&tm=30d&SUBMIT1.x=112&SUBMIT1.y=13&ss=0&TabNum=1&rc=3
Contact: Questions may be directed to Kenneth Wilson at the USDA APHIS Human Resources Office at 301 734 8428; fax: 301 734 4984; e-mail: Kenneth.Wilson@APHIS.USDA.gov
Posted 7 February 2008
Department of Chemistry Western Michigan University |
Analytical Chemistry FACULTY POSITION
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The Department of Chemistry, Western Michigan University (WMU) is seeking tenure track position at the Assistant Professor level pending budgetary approval. Area of interest is Analytical Chemistry. A Ph.D. degree in chemistry with postdoctoral experience and publication record is required. The candidate will be expected to maintain a vigorous research program with external funding and teach undergraduate chemistry courses and graduate courses in their area of specialization. The Carnegie Foundation for the Advancement of Teaching has placed WMU among the 76 public institutions in the nation designated as research universities with high research activity. WMU is an affirmative action/equal opportunity employer consistent with applicable Federal and State Law.
All qualified applicants should visit http://www.wmich.edu/hr/careers-at-wmu.htm to apply. Online applications should include a letter of application, curriculum vitae, description of research plans and teaching philosophy. Graduate transcripts and three letters of recommendation can be sent directly to Chair Chemistry Search Committee, Department of Chemistry, Western Michigan University, Kalamazoo, MI 49008-5413. For more information visit our website at http://www.wmich.edu/chemistry or email chem-chair-search@wmich.edu. Screening of applications will begin on February 15, 2008 and continue until the position is filled.
Posted 7 February 2008
Unigen Pharmaceuticals |
POSITION DIRECTOR, NATURAL PRODUCTS
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Unigen Pharmaceuticals, Inc. (www.UnigenUSA.com) is a leading natural products research and development company and proprietary ingredients supplier. The company is dedicated to the discovery of botanically derived drugs and bioactive natural ingredients that address consumer health and beauty needs and help improve the quality of human life. We are seeking a self-motivated individual with an ability to lead a group of natural product scientists for rigorous research in the areas of discovery and development of bioactive natural products.
POSITION: DIRECTOR, NATURAL PRODUCTS (Code: DNP)
This position requires a strong organizational leader who committed to technical excellence, team build-up, collaborative communication, career development of team members and corporate success oriented approach. The successful candidate will lead a multidisciplinary team responsible for collection of natural materials, preparation of extracts, fraction and compound library, application of state-of-the-art NMR, LC/MS/MS, GC/MS and other spectroscopic technology for structure dereplication and elucidation, and growth of an informatics database. The successful candidate will work closely with screening and development groups for therapeutic target selection, high-throughput molecular or cell based assay guided active isolation; lead compounds pre-clinical and clinical development and commercialization. Finally, the successful candidate will support product launch and business-to-business license, provide chemical test results, data interpretation, and technical input to the business development team.
Requires a Ph.D. in natural product chemistry with 8 + yrs academic or industry exp, preferably in natural product drug discovery. A proven record of technical supervision and success in R&D project management are essential. A solid background in professional presentations and publications in peer-reviewed journals is required. Knowledge and experience in physiology, pharmacology, human nutrition, drug discovery and development, data management system and bio-informatics are strongly recommended. Must be a team player with excellent verbal and written communication skills.
Unigen is located in Lacey, Washington, which is south of Seattle and neighboring Olympia - Washington’s capitol city. We offer competitive salary, a comprehensive benefits program including 401K (with company match), health insurance, life insurance, and an opportunity for career growth and advancement in a dynamic work environment. We invite qualified applicants to send their resume, including salary history / requirements and references to: Director, Human Resources, Unigen Pharmaceuticals, Inc. 2660 Willamette Drive, NE, Lacey, WA, 98516 or fax same to (360)-413-9135. Unigen is an equal opportunity employer.
Posted 7 February 2008
Post-Doctoral Research Associate Natural Products Drug Discovery |
Department of Medicinal Chemistry University of Utah |
The Department of Medicinal Chemistry at the University of Utah is seeking a post-doctoral research associate.
This research will be performed in Professor Chris M. Ireland’s laboratory in Salt Lake City, Utah. The candidate will be part of a multidisciplinary team with a major focus on anticancer drug discovery and will require good communication skills.
The position will focus on isolation and structure elucidation of bioactive molecules from marine invertebrates. Extensive experience with HPLC and modern NMR spectroscopic techniques is required. Experience with LCMS is desired. Applicants must have a recent PhD in natural products chemistry or a closely related discipline. This is a one-year appointment, renewable based on satisfactory job performance and availability of funds.
The Department has three high field NMR spectrometers (400, 500, and 600 MHz) equipped with a variety of probes including a 3 mm microprobe and a 5 mm cryoprobe, as well as modern mass spectrometers including a Q-tof micro in Professor Ireland’s lab.
The Immigration Reform and Control Act requires employment eligibility certification for all employees. All job offers are contingent upon completion of the I-9 verification process.
Send a resume and contact information for three references to:
Dr. Tim S. Bugni
University of Utah
Department of Medicinal Chemistry
30 S 2000 East, 309 Skaggs Hall
Salt Lake City, UT 84112
Posted 1 February 2008
Natural Products Chemist or |
The Walker Cancer Research Institute, Inc |
NATURAL PRODUCTS DRUG DISCOVERY The Walker Cancer Research Institute, Inc., a non-profit organization dedicated to the discovery of natural product anticancer agents, announces an opening for a Ph.D. Natural Products Chemist, Medicinal Chemist or equivalent. Required duties will include: performing bioassay-guided fractionation, isolation, purification and structure determination, and performance of cell culture bioassays. Appointment is for one year with possibility of extension. Salary based on qualifications and experience. Please submit resume, list of publications, research accomplishments and two recent letters of reference to:
Elsa Pilarinou
Director, WCRI (Florida Division)
1634 Metropolitan Blvd.
Tallahassee, FL 32308.
Posted Nov. 2, 2007
Research Scientist |
Bionovo, Inc. |
Bionovo, Inc. is currently seeking a motivated individual with strong interpersonal skills and a background in multi-step organic synthesis of natural products to assist in its discovery group. The position will focus on the de novo synthesis of lead compounds isolated from plants and developing analogs for SAR studies. A strong analytical chemistry background and applicable postdoctoral and/or industry experience are required. Familiarity with Waters HPLC systems, Agilent LC/MS, and Varian NMR is a plus.
Please submit a cover letter, CV, and references to Bionovo Inc, Human Resources Dept, 5858 Horton St Suite 375 , Emeryville , CA 94608 or via email to synthesis@bionovo.com . More information about Bionovo and employee benefits can be found at www.bionovo.com.
Posted Nov. 2, 2007
Research Associate in Natural Products |
Dept of Biological Sciences Lehman College , CUNY |
Seeking a Ph.D.- level natural products chemist to analyze constituents from plant sources. Candidates should have experience in the isolation and structural elucidation of bioactive natural products. Expertise with various chromatographic techniques including quantitative analysis by HPLC-PDA and LC-MS is essential. Expertise in conducting NMR experiments and interpreting spectra is also required.
Lehman College is a pleasant tree-lined, self-enclosed campus of CUNY located in the northern Bronx, about 12 miles from midtown Manhattan . The phytochemistry laboratory at Lehman College , CUNY is a modern state-of-the-art facility with outstanding HPLC, LC-MS, and NMR capabilities. Please send cover letter and resume to Professor Edward J. Kennelly at www.rfcuny.org/hr/pvn/cgi-bin/show_job.asp?pvn=REA-589.
Posted Sept. 24, 2007
Independent Chemistry Experts |
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Join a virtual multidisciplinary project team consulting to industrial and academic sponsors, who are developing naturally-occurring complex, heterogeneous products (oils, extracts, polymers, proteins, etc.) for medicinal purposes.
Note: This opportunity is NOT salaried employment; nor is it a research or lab-bench position.
Ideal Candidate:
- Experienced (post-doctoral, or equivalent) in the Chemistry of complex heterogeneous naturally-derived products.
- Capable of critically evaluating data and methods.
- Maintains “cutting-edge” knowledge of methods and techniques.
- Self-motivated, well organized and meets deadlines.
- Good “people skills”
- Enjoys working in a collaborative multidisciplinary setting.
- Communicates well both in writing and verbally.
- Likes flexible hours and work location.
- Willing to travel internationally.
- No “conflicts of interest” with any current employment.
- Per hour compensation (independent contractor)
Required Experience:
- PhD or similar degree in Chemistry (e.g., Organic or Biochemistry, Medicinal Chemistry, Natural Products Chemistry).
- Knowledgeable of extraction, fractionation of complex heterogeneous naturally-derived products.
- In depth experience with a wide range of analytical methods and techniques.
- “Computer-literate” in Word, Power Point, e-mail, Internet Searching, etc.
Desirable Experience:
- Prior experience with FDA and/or US regulatory applications (e.g., INDs/NDAs/BLAs - Chemistry-Manufacturing-Controls, GMPs, etc.).
- Experience in working on collaborative projects with industrial and/or academic partners.
- International experience.
Please submit a complete CV, inquiries and contact information (telephone and e-mail) to: pancot@verizon.net . This is not a single position; all qualified individuals will be considered.
Posted September 11, 2007
Faculty Postions |
Dept. of Pharmaceutical Sciences |
The University of Hawaii at Hilo invites applicants for faculty positions in their new College of Pharmacy . Each of the positions listed below are immediately available for full-time (11 month appointments), tenure track appointments. The University reserves the right to hire at any rank depending on the qualifications of the selected applicants. All faculty are expected to develop an extramurally-funded research program, be involved in scholarly activities, contribute to the PharmD curriculum, serve as a faculty advisor for PharmD students, and provide service to the College and University by serving on appropriate committees. Excellent communication skills and the ability to function in a team environment are essential qualities of these positions.
Three full-time faculty positions are available in the Dept. of Pharmaceutical Sciences (one in medicinal chemistry, one in pharmaceutics and one in pharmacology) at the assistant, associate or full professor rank. A PhD degree in the respective discipline is required or Pharm D or other doctoral degree with equivalent training. Preference will be given to candidates who have a pharmacy background and two or more years experience in academic pharmacy. Successful candidates will contribute to the appropriate pharmaceutical sciences lectures and laboratory components of the PharmD curriculum. All faculty members will be expected to contribute to the scholarly pursuits of the department in basic and applied research. It is expected that all new faculty will either have or will develop a research program that is complementary to those already existing within the department.
The review of applications will begin immediately and continue until the positions are filled. Rank and salary are highly competitive and commensurate with qualifications and experience. Interested candidates are invited to submit a letter of intent and provide their philosophy of teaching and research, a curriculum vitae and contact information for 3 professional references to the Chair of the search committee.
For full details of the positions and application requirements, link to: http://www.uhh.hawaii.edu/uhh/hr/jobs.php
Contact Information
Anthony D. Wright, PhD
Associate Professor and Chair
Department of Pharmaceutical Sciences
College of Pharmacy
University of Hawaii at Hilo
60 Nowelo Street – Suite 101
Hilo , HI 96720
1 (808) 443-5900
adwright@hawaii.edu
Posted August 31, 2007
Health Scientist Administrator |
NCCAM-DEA |
Job Announcement Number: NCCAM-07-207683-CR-DE
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Posted August 31, 2007
COP Postdoctoral Fellow NPDD |
Dept of Pharmaceutical Sciences |
Regular, Full-Time, Limited Term (approximately twelve (12) months in duration), RCUH Non-Civil Service position with the College of Pharmacy (COP), Department of Pharmaceutical Sciences, located in Hilo, Hawaii. Continuation of employment is dependent upon program/operational needs, satisfactory work performance, and availability of funds. Minimum Monthly Salary: $3,222.00.
Duties: Assist in managing the day-to-day organization of an Assistant Professors research program in the areas of biology-driven natural product drug discovery, with emphasis in the fields of cancer chemotherapy and cancer chemoprevention. Minimum Qualifications: Education: Doctorate from an accredited college or university.
Experience: Two to four (2-4) years of relevant experience, which includes graduate thesis work. The position requires experience in the isolation and structure elucidation of natural products. Abil/Know/Skills: Knowledge of scientific writing to prepare manuscripts, reports, and knowledge in structure elucidation of natural products are essential. Professional communication skills, written and oral. General computer skills, using numerous software programs: Microsoft Office (Word, Excel, PowerPoint, and Access); Endnote; Photoshop. Full understanding of confidentiality. The position requires proficiency in high performance liquid chromatography (HPLC) techniques, and in the interpretation of the resulting data. Desirable
Qualifications: Ph.D. from an accredited college or university in Natural Products Chemistry, Pharmacognosy, Organic Chemistry or a related field. Experience working in a University environment. At least two (0-2) years of experience (which includes graduate thesis work) with the following: structure determination of natural products; bioassay guided isolation and separation skills including HPLC and medium pressure liquid chromatography (MPLC). Experience with the synthesis.
Inquiries: Elizabeth Ryan 443-5900 ( Hawaii ). Application Requirements: The preferred method of applying for a job is through our on-line application process. Please go to www.rcuh.com, click on Employment and navigate to Job Announcements/Apply for a Job. However, if you do not have access to the Internet, you may apply by submitting resume; cover letter including Recruitment ID#, referral source, narrative of your qualifications for position and salary history; names, phone numbers and addresses of three supervisory references and copy of degree(s)/transcripts/certificate(s) to qualify for position by fax (808) 956-5022 or mail to Director of Human Resources, Research Corporation of the University of Hawaii, 2530 Dole Street, Sakamaki Hall D-100, Honolulu, HI 96822 before the closing date. EEO/AA Employer.
Posted August 28, 2007
Postdoctoral Research Assistantship |
Dept of Chemistry |
The Chemistry Department at Vanderbilt is seeking a highly motivated Post-doctoral Research Associate for the isolation and structure elucidation of natural products from privileged microbial sources. Example of microbes of interest will be novel actinomycetes and myxobacteria harvested from highly unusual environments. This position will provide an opportunity for a researcher with experience in natural product isolation and structure elucidation to participate in establishing a cutting-edge program in natural product discovery. Vanderbilt has access to a wide variety of resources for natural products discovery. Including A state of the art small molecule NMR facilities containing a new Brüker 600 MHz cryoprobe LC/NMR, 500 MHz, two 400 MHz and 300 MHz instruments., a world class mass spectrometry facility with access to over ten HPLC/MS/MS instruments for small molecule analysis, a robotic high-throughput screening facility staffed with industry veterans in high-throughput bioassay design and implementation.
Applicants must have extensive experience in bioactivity guided purification of natural products and a proven track record in structure elucidation of complex natural products using modern spectroscopic methods, including 1D, 2D-NMR and mass spectroscopy. Interested applicants should send a letter of intent and CV to brian.bachmann@vanderbilt.edu . Applications will be considered until the position is filled.
Posted August 13, 2007
Health Scientist Administrator |
NCCAM |
The National Center for Complementary and Alternative Medicine (NCCAM) seeks talented, knowledgeable, and motivated candidates for a Health Scientist Administrator in the Division of Extramural Research and Training at the National Institutes of Health in Bethesda, Maryland. Applicants must have successfully completed requirements for a Ph.D., M.D. (or equivalent doctoral degree), in an accredited college or university, including acceptance of the dissertation, in an academic field of health or pertinent sciences allied to health or health-related research.
Apply to this announcement through the USAJOBS Web site.
Posted June 29, 2007
Research Assistantships Marine Natural Products Chemistry |
Hawaii Pacific University |
The College of Natural Sciences of Hawaii Pacific University, Kaneohe , Hawaii , has competitive research assistantships available in marine natural products chemistry within our interdisciplinary Master of Science in Marine Sciences degree program. HPU, the largest private university in the state, is located on the island of Oahu , providing outstanding access to marine environments. Research assistantship duties and responsibilities will include conducting research on secondary metabolites from marine microbes or invertebrates while working towards an advanced degree. At a minimum, applicants should have a B.S. degree from an accredited institution, an u ndergraduate grade point average of 3.0 or higher, and good performance on the Graduate Record Examination (see www.hpu.edu/msms for complete admissions requirements). Applicants must apply to the HPU graduate program (see previous link) and separately submit a CV, transcripts, and list of 3 references to Dr. F. David Horgen, College of Natural Sciences , Hawaii Pacific University, 45-045 Kamehameha Highway , Kaneohe , Hawaii 96744 , E-mail: dhorgen@hpu.edu . Applications will be considered until filled. Inquiries on the research assistantships should be made to Dr. Horgen, while inquiries on the graduate program should be made to Dr. Alissa Arp, Dean and VP for Research, at the same address (E-mail: aarp@hpu.edu ).
Posted June 29, 2007
Senior Research Scientist Chemical and Screening Sciences |
Wyeth Research Princeton, NJ |
Position Description and Responsibilities : Become a member of the Wyeth Discovery Metabolite Identification Team. Work closely with mass spectrometrists, biotransformation chemists, and NMR spectroscopists to assist in microsomal incubation of synthetic lead compounds, purification of microgram quantities of metabolites and structure elucidation of the metabolites by LC/MS/MS and NMR. High productivity, demonstrated expertise at purification and handling of small quantities of compound, and strong structure elucidation skills are an essential part of this function. An emphasis for this position is productive and efficient purification of metabolites. The ability to work effectively and communicate well in a team setting is also essential.
Position Requirements : The successful candidate will have a PhD with an emphasis in Chemistry, Natural Products, or Metabolism and 1 year of experience, an MS with a minimum of 6 years of experience, or a BS with a minimum of 8 years of experience.
For more information and to apply online, please visit us at: www.wyeth.com/careers
For specific questions, please contact: mcconno@wyeth.com
Posted June 6, 2007
Postdoctoral Researcher Natural Product Chemistry and Pharmacognosy |
LSU AgCenter Baton Rouge, LA
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(This is a one-year, grant-funded, non-tenure track position. Continuation will be dependent on funding, job performance, and continued need for the appointment.)
WORK LOCATION: School of Renewable Natural Resources, LSU Agricultural Center, Baton Rouge, Louisiana.
NATURE OF WORK: This position will be responsible for developing HPLC methods for fingerprinting analysis of bioactive extracts, isolating bioactive compounds, characterizing bioactive extracts, and developing standardization protocols. This is a project approved for funding by NIH for two years. The successful candidate will be required to prepare reports and manuscripts for publications.
QUALIFICATION REQUIREMENTS: Applicant must hold a Ph.D. in natural product chemistry, Pharmacognosy, or a related field. Applicant must possess experience in some, or preferably all, of the following (1) ability to develop optimal analysis methods for bioactive plant extracts, (2) experience with isolation of active compounds from traditional herbal remedies, (3) demonstration of skills and quality of fingerprinting analysis of plant extracts in manuscripts or publications, (4) demonstration of structural elucidations, (5) experience with bioactivity directed fractionation, (6) skills in developing standardization protocols for plant extracts, and (7) knowledge of separation sciences with various adsorbent materials.
SALARY AND BENEFITS: Salary will be commensurate with qualifications and experience. The LSU AgCenter has an attractive benefits package with a wide variety of benefit options. Benefits offered include retirement, multiple medical insurance options, supplemental insurances (dental, life, long-term disability, accident, vision, long-term care, etc.), Tax Saver Flexible Benefits Plan (saves tax dollars on some child care and medical expenses), university holidays (14 per year, typically includes a week off at Christmas), generous annual (vacation) and sick leave benefits, Employee Assistance Program, and possible educational leave and tuition exemption for coursework at campuses of the LSU System. Specific benefits depend on job category, percent effort and length of employment.
APPLICATION DEADLINE: June 15, 2007 or until suitable candidate is located.
DATE AVAILABLE: Upon completion of interview process.
APPLICATION PROCEDURE: Send a letter of application, CV, transcripts and contact information for three references, via email or fax, to:
Dr. Zhijun Liu
School of Renewable Natural Resources
Louisiana State University Agricultural Center
Baton Rouge , Louisiana 70803 USA
Phone: 225-578-4214; Fax: 225-578-4227
E-mail: zhiliu@lsu.edu
Web site: www.lsuagcenter.com
Posted June 6, 2007
NMR Scientist |
Unigen Pharmaceuticals Lacey, WA |
Unigen Pharmaceuticals, Inc. ( www.UnigenPharma.com ) is a leading natural products research and development company and proprietary ingredients supplier. The company is dedicated to the discovery of botanically derived therapeutic compounds and bioactive dietary supplements that address consumer health needs and work to improve the quality of human life. We are seeking a motivated individual with the desire and ability to perform rigorous science in the area of natural product structure elucidation.
POSITION: NMR SCIENTIST (Code: NMRS)
The successful candidate will work in a multidisciplinary team responsible for collection and interpretation of NMR data for structure elucidation of novel natural & synthetic compounds. The candidate will apply state-of-the-art NMR, LC/MS/MS technology, ACD, and informatics databases for structural analysis of bioactive compounds isolated from a collation of thousands of plant and marine specimens. Requirements include a Ph.D. degree in organic chemistry, physical organic chemistry or natural product chemistry with five+ years post-graduate research experience. A demonstrated and documented record of maintaining and managing high-field NMR equipment and a proven record of successful structure elucidation of complex natural products is essential. The successful candidate must have a thorough understanding of spectroscopy including modern 1D and 2D NMR, MS, LC-MS, UV, and IR. A proven record of assigning relative and absolute stereochemistry of natural products through spectroscopic, degradation and derivatization methods is desired. A solid background in chromatographic separation (HPLC, LC/MS/MS, GC/MS) and broad knowledge in biochemistry, analytical chemistry and computer science is required. As we operate in a team working environment, all employees must be team players with strong oral and written communication skills coupled with independent research abilities, being resourceful and able to work with minimal supervision.
Unigen is located in Lacey, Washington which is south of Seattle and neighboring Olympia which is Washington 's capitol city. We offer competitive salary, a comprehensive benefits program including 401K (with company match), health insurance, life insurance, and an opportunity for career growth and advancement in a dynamic work environment. We invite qualified applicants to send their resume, including salary history / requirements and references to: Director, Human Resources, Unigen Pharmaceuticals, Inc. 2660 Willamette Drive, NE, Lacey, WA, 98516 or fax same to (360)-413-9135. Unigen is an equal opportunity employer.
Posted May 17, 2007
Postdoctoral Researcher
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Dept of Chemistry & Biochemistry University of California, Santa Cruz |
The University of California, Santa Cruz invites applications for a postdoctoral position in the Department of Chemistry and Biochemistry under the direction of Professor Roger Linington. The laboratory focuses on the uses of secondary metabolites from marine-obligate bacteria as a source of small molecule diversity for drug discovery for tropical infectious diseases and the application of natural products as tools for understanding complex biological systems.
For more information about the Linington lab, please visit: http://www.chemistry.ucsc.edu/faculty/linington.html
RANK: Postdoctoral Scholar - Employee
SALARY: Starting at $32,304, commensurate with qualifications.
MINIMUM QUALIFICATIONS: Ph.D. or equivalent in Chemistry or closely related field.
PREFERRED QUALIFICATIONS: Experience with solid phase synthesis, development of new synthetic methodologies, bioassay guided natural products isolation and structural elucidation; advanced 2D NMR; and acquisition and interpretation of LC-MS data. Experience with the synthesis and purification of fluorescent small molecules and a SCUBA certification are desirable but not required.
TERM OF APPOINTMENT: One year, with the possibility of extension, contingent upon availability of funding and positive performance evaluation.
POSITION AVAILABLE: From August 15th 2007 (start date is negotiable).
APPLY TO: Applicants should send a CV, summary of research interests, and three letters of recommendation* electronically to rliningt@ucsc.edu Or by mail to:
Professor Roger Linington
Chemistry and Biochemistry Department
Physical Sciences Building, Room 346
University of California
1156 High Street
Santa Cruz, CA 95064
Please refer to position #T07-43 in all correspondence.
(*All letters will be treated as confidential. Please direct your letter writers to UCSC’s Confidentiality Statement.)
CLOSING DATE: This position is open until filled. Initial consideration of applications will begin on June 1, 2007.
The University of California, Santa Cruz is an Affirmative Action/Equal Employment Opportunity Employer, committed to excellence through diversity. We strive to establish a climate that welcomes, celebrates, and promotes respect for the contributions of all students and employees.
Inquiries regarding the University’s equal employment opportunity policies may be directed to: Equal Employment Opportunity/Affirmative Action Office at the University of California, Santa Cruz, CA 95064; (831) 459-2686. Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986.
If you need assistance due to a disability please contact the Academic Human Resources Office at 499 Clark Kerr Hall (831) 459-4300. This position description is available in alternate formats, which may be requested from Academic Human Resources at (831) 459-4300.
VISIT THE AHR WEB SITE http://www2.ucsc.edu/ahr
Posted May 8, 2007
Postdoctoral Researcher
|
Dept of Chemistry & Biochemistry University of California, Santa Cruz |
The University of California, Santa Cruz invites applications for a postdoctoral position in the Department of Chemistry and Biochemistry under the direction of Professor Roger Linington. The laboratory focuses on the uses of secondary metabolites from marine-obligate bacteria as a source of small molecule diversity for drug discovery for tropical infectious diseases and the application of natural products as tools for understanding complex biological systems.
For more information about the Linington lab, please visit: http://www.chemistry.ucsc.edu/faculty/linington.html.
RANK: Postdoctoral Scholar - Employee
SALARY: Starting at $32,304, commensurate with qualifications.
MINIMUM QUALIFICATIONS: Ph.D. or equivalent in Marine Microbiology or closely related field.
PREFERRED QUALIFICATIONS: Expertise in the isolation and fermentation of a wide range of classes of bacteria, ability to perform 16S RNA analysis for phylogenetic identification; familiarity with a variety of culturing techniques, including different solid and liquid media conditions; and enthusiasm for exploring new methods for the isolation and fermentation of marine bacterial species. An interest in field collections, SCUBA diving, and experience in the collection and handling of marine sediment cores is a plus but is not required.
TERM OF APPOINTMENT: One year, with the possibility of extension, contingent upon availability of funding and positive performance evaluation.
POSITION AVAILABLE: From August 15th 2007 (start date is negotiable).
APPLY TO: Applicants should send a CV, summary of research interests, and three letters of recommendation* electronically to rliningt@ucsc.edu. Or by mail to:
Professor Roger Linington
Chemistry and Biochemistry Department
Physical Sciences Building, Room 346
University of California
1156 High Street
Santa Cruz, CA 95064
Please refer to position #T07-42 in all correspondence.
(*All letters will be treated as confidential, please direct referees to the UCSC Confidentiality Statement.)
CLOSING DATE: This position is open until filled. Initial consideration of applications will begin on June 1, 2007.
The University of California, Santa Cruz is an Affirmative Action/Equal Employment Opportunity Employer, committed to excellence through diversity. We strive to establish a climate that welcomes, celebrates, and promotes respect for the contributions of all students and employees.
Inquiries regarding the University’s equal employment opportunity policies may be directed to: Equal Employment Opportunity/Affirmative Action Office at the University of California, Santa Cruz, CA 95064; (831) 459-2686. Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986.
If you need assistance due to a disability please contact the Academic Human Resources Office at 499 Clark Kerr Hall (831) 459-4300. This position description is available in alternate formats, which may be requested from Academic Human Resources at (831) 459-4300.
VISIT THE AHR WEB SITE http://www2.ucsc.edu/ahr
Posted May 8, 2007
Postdoctoral Research Associate Natural Product-Based Antitumor Drug Discovery |
Dept. of Pharmacognosy The University of Mississippi Oxford, MS |
Qualifications: Highly self-motivated individual with a Ph.D. degree in Natural Products Chemistry or closely related discipline; good verbal and written communication skills; ability to work with faculty and other researchers. Experience in bioassay-guided isolation and structure elucidation of chemically unstable natural products from terrestrial or marine organisms is required. Applicant should have experience supervising and helping graduate research assistants.
Duties: Isolation and structure elucidation of small molecules that inhibit HIF-1, STAT-3 and other antitumor molecular targets, through the use of bioassay-guided methods; this includes the special handling of chemically unstable natural product materials and the use of non-traditional chromatographic media; prepare reports/manuscripts; supervise and help instruct graduate students in natural products-related techniques.
Review of Applications: Begins Immediately. However, the position is open until filled or until an adequate applicant pool is reached.
Application Procedures: Interested individuals should submit a letter of application, a curriculum vita, and the names, addresses and telephone numbers of three persons, who may be contacted for letters of reference. Applications should be submitted via the University of Mississippi 's online employment site at https://jobs.olemiss.edu (From the UM employment web site select “Search Postings” on the left hand side toolbar; search under Department – “Pharmacognosy”; select position #10967428-050107 to review position and apply).
Nagle Laboratory: http://www.pharmacy.olemiss.edu/pharmacognosy/Nagle/Nagle.html
*This position is contingent upon funding.
The University of Mississippi is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA employer
Posted May 7, 2007
Marine Natural Product Chemistry/Organic Chemistry Research Officer |
NRC Institute for Marine Biosciences (NRC-IMB) Halifax , Nova Scotia Canada |
NRC is a dynamic, nationwide R&D organization committed to helping Canada realize its potential as an innovative and competitive nation. Our strengths are: outstanding people, core science and engineering expertise and information, research programs focused on key technologies and technology diffusion. Combining our strengths with those of industrial and academic partners, we foster Canada 's emerging national system of innovation.
You can make a difference at NRC!
The NRC Institute for Marine Biosciences (NRC-IMB) is respected worldwide for its research and technology development in marine biosciences, including state-of-the-art analytical chemistry of biological molecules. NRC-IMB features a broad and integrated suite of marine bioscience and biotechnology laboratories and an aquaculture research station. NRC-IMB is an integrated systems biology institute with the capability to investigate research questions from the level of the genome to the whole organism.
Your Challenge
This position supports the mission of NRC and the IMB with R&D activities of international scientific and technological calibre for developing a research program, relevant to industries involved in production of novel marine-based products in Atlantic Canada, including those destined for health and wellness applications. The primary focus of this position is to carry out research as part of IMB's Atlantic Initiative in support of the local life sciences cluster, which is focused on novel, high value marine by-products that provide substantiated health benefits to consumers. The research program will involve collaboration with the research and development sector, to foster growth of the domestic sector and promote export of Canadian products.
Within the Atlantic Initiative program at IMB, the incumbent will carry out advanced and innovative R&D research to develop marine-based products (e.g. lipids, antioxidants, peptides, vitamins) for functional food and nutraceutical applications, as well as other applications relevant to health. Linkages with IMB's expertise in molecular biology, biochemistry, proteomics, metabolomics, analytical chemistry and INH's expertise in animal models of disease will be strongly encouraged. Contributions and findings will promote the development of the research capacity in the local life sciences cluster and help to identify bioactive compounds in products from a variety of sources, primarily marine. The incumbent's program will be developed through internal and external funding and core facility support.
Duties may also include some organic synthesis and chemical modification, and the design and interpretation of experiments for the investigation of metabolic and biochemical processes. He/she will be encouraged to collaborate with IMB and external researchers in both core and revenue-generating projects within the mandate of the laboratory and the Atlantic Initiative, and to provide advice and assistance where appropriate to other groups, partners and industries.
The position may include the supervision of technical staff, postdoctoral fellows, visiting scientists and students. The incumbent will be responsible for dissemination of his/her research accomplishments through publication in high quality journals and presentations at national and international levels or through the development of intellectual property.
Your Credentials
Education
A PhD in natural products or organic chemistry or related discipline is required. Candidates who possess an equivalent combination of education and expertise may also be considered
Experience
Post-doctoral experience or equivalent in the extraction, fractionation, isolation and structural elucidation of natural products. This should be substantiated by publications in refereed journals, and/or patents, etc.
In depth experience with a wide range of analytical methods.
Experience in organic synthesis or semi-synthetic operations.
Experience in the application of chromatographic methods to the isolation and monitoring of bioactive compounds.
Experience in acquiring competitive funding from national or international agencies or contracts with private partners is essential.
Experience in working on collaborative projects with academic and/or industrial partners would be considered an asset.
Demonstrated experience in supervising technical staff and/or students.
Salary Range
This position is classified as a Research Officer (RO), a group that is unique to the NRC. The RO group uses a person-based classification system instead of the more common duties-based classification system. Candidates are remunerated based on their expertise, skill, outcomes and impacts of their previous work experience. The salary scale for this group is vast, from $49,489 to $116,915 per annum, which permits for employees of all levels from new graduates to world renowned experts to be fairly compensated for their contributions. In addition, an incumbent occupying a position within the RO Groups is currently entitled to receive a terminable allowance of $8,000 per year.
To apply
For further information including complete screening and assessment criteria (Reference number 63-06-42) and instructions on how to apply on-line, refer to the website: http://careers-carrieres.nrc-cnrc.gc.ca by 13 May 2007.
Vous pouvez obtenir ces renseignements en français au http://carrieres-careers.cnrc-nrc.gc.ca .
NRC is committed to employment equity. We thank all those who apply and advise that only those selected for further consideration will be contacted.
Posted April 27, 2007
Post-Doctoral Research Position Natural Products Chemistry |
Chemistry Dept. University Of Wisconsin-La Crosse La Crosse , WI |
A postdoctoral research internship is available to begin summer or fall 2007. Appointment is for one year with possibility for extension up to three. Applicants must possess a Ph.D. in organic, medicinal, or natural products chemistry, solid communication skills, and an ability to independently manage multiple research projects involving the isolation, purification, and structure elucidation of bioactive natural products (primarily from wild fungi). Preference will be given to candidates with significant experience in 1D and 2D NMR and structure elucidation. Also desirable is experience with bioassay-guided fractionation methods. Applicants should submit a letter of intent (including recruitment number #08-CHM-01) , a curriculum vitae , undergraduate and graduate transcripts, a summary of research accomplishments, and have a minimum of two original letters of reference sent to: Prof. Aaron Monte, Chair, Department of Chemistry, University of Wisconsin-La Crosse , La Crosse , WI 54601 . Application files completed by May 11, 2007 will be given highest priority.
Posted April 27, 2007
Post-doctoral Position Marine Natural Products Chemistry |
Hawai‘i Pacific University Kaneohe , HI |
The Laboratory of Marine Biological Chemistry in the College of Natural Sciences at Hawai‘i Pacific University has an immediate opening for a NIH-funded Post-doctoral Associate in the area of marine natural products chemistry. The successful applicant will join recently initiated projects aimed at the discovery and characterization of small molecules from marine microbes and invertebrates that modulate the function of transient receptor potential cation channels. Bioactivity is assessed in protein over-expression systems and electrophysiological experiments. Candidates must have a Ph.D. (by June 2007) in Organic Chemistry, Biochemistry, Pharmacognosy, or related field and a strong background in HPLC, NMR, and LC-MS. Candidates should be self-motivated, capable of working independently, and possess a strong record of research productivity. Good verbal and written communication skills are essential. Desirable qualifications include experience in one or more of the following areas: (1) isolation and characterization of secondary metabolites, (2) ion channel biology, (3) cell and microbial culture, and (4) research diving.
Hawai‘i Pacific University ( www.hpu.edu ), the largest private university in the state, is located on the island of O ‘ahu, which offers an outstanding climate, an exciting urban environment, and ample access to a wide range of outdoor activities.
To apply, submit C.V. and 3 well-selected references to Human Resources: 1136 Union Mall, Suite 208 Honolulu, Hawai`i 96813. Phone: (808) 544-1189. FAX: (808) 544-1192. E-mail: hr@hpu.edu EOE. Website: www.hpu.edu/employment . For inquiries contact Dr. David Horgen, Associate Professor, College of Natural Sciences at dhorgen@hpu.edu . Full consideration will be given to applications received by May 25, 2007.
Posted April 25, 2007
Postdoctoral Research Associate Molecular-Targeted Anticancer Research |
Dept. of Pharmacognosy School of Pharmacy |
Qualifications: Ph.D. degree in Molecular and/or Cell Biology, Biochemistry, Cancer Biology or related discipline; good verbal and written communication skills; ability to work with faculty and other researchers. Experience in mammalian molecular biology or biochemistry is required. Applicant should have experience supervising and helping graduate research assistants.
Duties: Perform tumor cell-based molecular biological, biochemical, and cell biological studies characterizing and investigating mechanisms of action of small molecules that inhibit hypoxiainducible factor-1 (HIF-1) and other antitumor molecular targets; prepare reports/manuscripts; supervise and help instruct graduate students in molecular biological, biochemical, and cell biological techniques.
Review of Applications: Begins Immediately. However, the position is open until filled or until an adequate applicant pool is reached.
Application Procedures: Interested individuals should submit a letter of application, a curriculum vita, and the names, addresses and telephone numbers of three persons, who may be contacted for letters of reference. Applications should be submitted via the University of Mississippi 's online employment site at https://jobs.olemiss.edu.
For Additional information regarding the position contact Dr. Dale G. Nagle at dnagle@olemiss.edu or Dr. Yu-Dong Zhou at ydzhou@olemiss.edu.
*This position is contingent upon funding.
The University of Mississippi is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA employer
Posted April 20, 2007
Manager of Product Development |
Novus International, Inc. St. Louis, MO |
BACKGROUND
Novus International, Inc., a global leader in the animal agriculture industry, is a privately held corporation headquartered in St. Louis , Missouri , with annual sales of approximately $500 million, approximately 300 employees worldwide, serving customers in more than 80 countries around the world. The Novus corporate mission is to help feed the world affordable, wholesome food by supplying superior goods and services to the leading commercial food producers worldwide.
POSITION SUMMARY
Reporting to the Head of the Chemistry and Analytical Services Group, the Manager of Product Development will be responsible for developing new natural and synthetic antioxidant product formulations for livestock, companion animal and human nutrition markets, and collaborating with colleagues in Marketing, Technical Service and Sales to support the application of existing antioxidant products with Novus customers. He/she will lead new product teams in early stages of discovery, research trials, customer trials, pilot scale production, and plant qualification through full-scale production and market development.
PROFESSIONAL CAPABILITIES AND BACKGROUND EXPERIENCE
§ Minimum of 5 years of experience in product development; specific experience related to antioxidant chemistry/biochemistry and analytical assay validation is a plus
§ Qualified candidates will have been published in peer reviewed journals, possess solid project management skills and excellent interpersonal and organizational skills
§ Candidates must possess a M.S. or Ph.D in Chemistry, Biochemistry or a relevant discipline
- Ability to work in cross-functional teams
- Well organized and an effective planner in use of resources while demonstrating flexibility and responsiveness as market needs dictate
- Computer proficiency in Word, PowerPoint, and Excel applications is required
Interested applicants should send a resume/CV with salary requirements to Adam Smith at asesc@verizon.net.
Posted April 10, 2007
Undergraduate Research Assistantships Summer/Fall 2007 |
The Smithsonian Tropical Research Institut Balboa Ancon, Panama |
We are looking for two upper-division undergraduate students or recent graduates for research assistantships in natural product drug discovery during the summer or fall of 2007 in the lab of Dr. Marcy J. Balunas at the Institute of Advanced Scientific Investigations and High Technology Services (INDICASAT) in conjunction with the Smithsonian Tropical Research Institute (STRI) in Panama City, Panama. The projects will be part of a U.S. National Institutes of Health (NIH) International Cooperative Biodiversity Group (ICBG) grant entitled “Ecologically Directed Drug Discovery in Panama” (Principal Investigator, Dr. William H. Gerwick, Scripps Institution of Oceanography).
Project Description: Treatments for tropical diseases are generally prohibitively expensive for many people living in areas of high rates of infection. Furthermore, many tropical diseases are developing resistance to currently available treatments, or are without effective treatments. Natural products contain highly diverse structures with unique characteristics not readily accessible through synthetic or combinatorial chemistry. Marine and plant species from the biologically diverse oceans and forests in Panama will likely yield chemically diverse compounds, some of which may inhibit the infection and/or spread of tropical diseases. This project involves:
• Using ecologically guided marine and plant collection techniques to collect specimens for screening;
• Extracting marine and plant specimens, performing pre-fractionation of extracts, and sending for screening for in vitro activity against tropical diseases including Dengue fever, malaria, Chagas disease, and leishmaniasis, as well as for cytotoxicity screening with in vitro cancer cells;
• Conducting bioassay-guided fractionation to isolate and identify compounds that act against these tropical diseases.
Students will be involved in many aspects of the research project, including collection, extraction, and bioassay-guided fractionation using various chromatographic and spectroscopic techniques.
Funding
Funding for these assistantships comes from the Minority Health and Health Disparities International Research Training (MHIRT) program funded through the National Center on Minority Health and Health Disparities (NCMHD). The MHIRT program is designed to increase the numbers of students belonging to health disparities populations or underrepresented minorities that pursue advanced degrees in basic sciences, biomedical or clinical research fields. Travel, food, lodging, and research expenses are completely covered and a small personal stipend is provided.
Program Eligibility:
• Students should belong to an ethnic minority including, but not limited to, African Americans, Hispanic Americans, Native Americans, Alaskan Natives, Native Hawaiians and Pacific Islanders, or rural Appalachians (non-ethnic females also qualify)
• Applicants must be U.S. citizens or permanent residents of the U.S.
• Students should be juniors, seniors, or recent graduates with a minimum GPA of 3.0
• Students should have completed at least one year of chemistry with laboratory
• Students must demonstrate interest in pursuing graduate research
• Students must spend a minimum of 3 months in Panama working on the project (4-6 months is preferred
To Apply: Send the following materials to Dr. Marcy J. Balunas at balunasm@si.edu:
1. Curriculum Vitae including name, permanent and current addresses, phone, e-mail, GPA, and complete educational and employment history (social security number and date of birth will be required upon acceptance to the program).
2. A 2-3 page essay including information on your background (e.g., family history, ethnicity, previous laboratory research, education, travel experience, etc.) and your career goals (including how you think a MHIRT assistantship will help you attain these goals).
3. Two letters of recommendation, including from someone who has directly supervised you in a laboratory setting (e.g., graduate student, technician, postdoctoral researcher, or professor). Letters of recommendation should be e-mailed directly to Dr. Balunas.
DEADLINE FOR SUBMISSION: Application review will begin May 1, 2007 and continue until positions are filled.
Posted April 10, 2007
Director or Vice President of Botanical Science & Regulation |
The Council for Responsible Nutrition Washington, DC |
REPORTS TO: President, Council for Responsible Nutrition
OBJECTIVE: To increase the awareness of the evolving botanical research base that supports an appropriate role for plant-based dietary supplements and to use that science as the basis for influencing and responding to regulatory and legislation initiatives, industry activities and media coverage of botanical and herbal dietary supplements
DUTIES AND RESPONSIBILITIES: Provides scientific expertise in botany, pharmacognosy and toxicology for evaluating issues related to current practices and viewpoints of opinion leaders. Evaluates proposed government or industry actions and recommends appropriate CRN positions and actions. Builds rapport with the botanical and natural products chemists communities on issues and identifies experts who can provide assistance to CRN on matters of concern. Exercises ingenuity and initiative in developing CRN position statements on botanical and herbal product issues and submitting comments to government agencies on proposed regulatory actions that impact plant-based dietary supplements. Ensures that CRN's legislative or other policy positions are based on a sound scientific rationale. Analyzes emerging research results and attempts to put new data into perspective for CRN members, for regulators and legislators, for the media, and for the public.
Builds cooperative and productive relationships with other trade, professional, and consumer organizations with an interest in dietary supplements and seeks to develop harmonious approaches on issues of mutual interest.
Monitors regulatory proposals and prepares comprehensive comments or other response reflecting CRN members' views on issues affecting herbals and botanicals. Provides formal and informal input to regulators on issues affecting the industry. Establishes ongoing effective networks with regulatory officials to facilitate communication. Ensures CRN members are fully aware of regulatory developments and that they are provided with an opportunity for input. Serves as a resource for CRN members on the current status of regulations and proposals, and on the interpretation of regulations, seeking input from regulatory officials or from counsel as appropriate.
Responds to CRN member requests for information and guidance on biochemistry, toxicology, pharmacology, technical, or regulatory issues as they relate to plant-based dietary supplements.
Organizes and provides staff support for CRN member working groups on botanical or regulatory issues. Organizes botanical/regulatory components of the CRN Annual Conference, The Workshop and other CRN-sponsored events.
Works with the CRN communications staff to heighten the visibility of positive information on the safety and benefits of dietary supplements. Serves as a credible spokesperson for CRN and the industry on relevant issues.
Education and Experience
- Doctor of Philosophy in Plant Biology, Organic Chemistry, Botany, Pharmacognosy, Toxicology or Natural Medicine or related discipline
- Minimum five years relevant experience in the field of Botanical Science or Natural Products Chemistry
- Familiarity with current federal regulation of dietary supplements
- Previous dietary supplement industry or FDA experience preferred
- Excellent written communication (with some history of publication in peer reviewed journals) and excellent oral presentation skills
- Ability to multi-task and work in collegial, fast-paced, fluid environment as a team player with other staff and with member company representatives
Posted March 12, 2007
ASSOCIATE SCIENTIST OR SR. RESEARCH ASSOCIATE |
Kemin Health Des Moines, IA |
Reports To: Holly Showalter, Ph.D. Senior Scientist, R&D
Overall Function: Actively participate in the front-end of the Product Innovation Process (PIP) within R&D at Kemin Health. Develop the technical proof of principle for projects and formulate new patentable technologies for Kemin Health. Develop new concept ideas for the dietary supplement ingredient market.
Major Responsibilities:
- Design and execute innovative research projects pertaining to the development of new products under consideration of most current scientific literature and business and economical goals.
- Develop new product ideas for PIP (Product Innovation Process)
- Collaborate with employees in attaining assigned research goals.
- Troubleshoot instrumentation problems as necessary
- Assist in identifying potential collaborations furthering business goals.
- Relate research effectively to business goals and create intellectual property with guidance
- Highly effective in communication, problem solving, and multi-tasking
- PhD in chemistry; or
- Masters degree in chemistry with